Objective: Chemotherapy is one of the important adjuvant methods for the treatment of glioblastoma (GBM), and chemotherapy resistance is a clinical problem that neurooncologists need to solve urgently.It is reported that Saikosaponin D (SSD), an active component of Bupleurum chinense, had various of antitumor activities and could also enhance the c
Cyclolinopeptide B methanol trisolvate
The title compound, C56H83N9O9S·3CH3OH, is a methanol trisolvate of the cyclolinopeptide cyclo(Met1—Leu2—Ile3—Pro4—Pro5—Phe6—Phe7—Val8—Ile9) (henceforth referred to as CLP-B), which was isolated from flaxseed oil.All the amino acid residues are in an l-configur
Characterization and differential gene expression between two phenotypic phase variants in Salmonella enterica serovar Typhimurium.
Salmonella enterica serovar Typhimurium strain 798 has previously been shown to undergo phenotypic phase variation.One of the phenotypes expresses virulence traits such as adhesion, while the other phenotype does not.Phenotypic phase variation appears to correlate with the ability of this strain to cause persistent, asymptomatic infections of swine
Imp is expressed in INPs and newborn neurons where it regulates neuropil targeting in the central complex
Abstract The generation of neuronal diversity remains incompletely understood.In Drosophila, the central brain is populated by neural stem cells derived from progenitors called neuroblasts (NBs).There are two types of NBs, type 1 and 2.T1NBs have a relatively simple lineage, whereas T2NBs expand and diversify the neural population with the generati